Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions. Take this medication by mouth, with food or milk to prevent stomach upset, as directed by your doctor. Take the tablet form of this medication with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. amitriptyline 10 mg reviews Methyl PREDNISolone Dose Pack is a steroid that prevents the release of substances in the body that cause inflammation. 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I also had a bad sinus headache in the evening not to mention a hard time sleeping because of a dry, hacking nighttime cough that woke me up -- I only get the cough at night. The first day I felt pretty bad mostly I think because the drainage was suppressing my appetite and making me feel nauseous. It starts out as allergy symptoms, gets into the sinuses a bit, but ends up settling in my chest where I end up with a tender sternum, horse voice, although not able to break anything loose For the past 3 yeasrs tehy've started me out on a z-pack and I've ended up on prednisone.......and what is going on? I went to the doctor on Sunday and he said I had an infection and prescribed a Z-pack and prednisone. (I have lots of sinus infections, have had surgery on my sinuses, etc.) Doc gave me a z-pack and prednisone. Suggested I try Claritin or zyrtec to see if allergies are triggering all of this. 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