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    Acyclovir and Valaciclovir are two antiviral drugs. Because these two are in the same class, their mechanism of action is similar. Acyclovir Acyclovir is an antiviral drug synthesized using the nucleoside extracted from the sponge Cryptotethya crypta. It is available in the market under many brand names. Acyclovir is a very commonly used drug, and the commonest indication is Herpes viral infections. It may be used in pregnancy if the benefits outweigh the risks only. The mechanism of action of acyclovir is complicated. Once the drug enters the body the viral enzyme called thymidine kinase converts it to acyclovir monophosphate. Then, cellular kinase enzymes convert it into acyclovir triphosphate. This final product blocks DNA replication and viral reproduction. Acyclovir is very effective against many species of herpes virus family, and resistance to the drug action is encountered very rarely. Therefore, if taken in tablet form the amount that reaches the blood is small. Therefore to obtain high concentrations, acyclovir should be given intravenous. Half-life is the time taken to reduce the concentration by half. UpToDate tadalafil manufacturers Overview of FIV and Gingivostomatitis Alzheimer's disease drug development pipeline
     
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