The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. Psychotropic meds chloroquine Hydroxychloroquine plaquenil oitcome for lupas patients Chloroquine treatement ich per gallon If you cannot take Plaquenil, there are other drugs that can help you. When you see your Rheumatologist, ask her what other drugs are available to treat your Sjogren's. You do not mention if you have stopped taking the Plaquenil. Plaquenil can cause a severe rash and allergic reaction. It’s used in people with Sjogren’s syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Surgery. A minor procedure to seal the tear ducts that drain tears from your eyes punctal occlusion might help relieve your dry eyes. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary. Scientists aren't certain why some people develop Sjogren's syndrome. Sjogrens plaquenil rash Symptoms of Sjogren's, Medications for Sjogren’s Syndrome NYU Langone Health Round hydroxychloroquineWhat is the effect hydroxychloroquine in arthritis Rashes that are associated with purpura blood spots can represent vasculitis, an inflammation of the blood vessels. Although these rashes are not as common as the ones discussed above, they are important to recognize in Sjögren’s patients and should be seen quickly by a dermatologist. Natalie Wright, MD, FAAD Ask the Expert Skin Rashes and Sjögren's - info.. Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic. Hydroxychloroquine User Reviews for Sjogren's. -. After many years on plaquenil, I got the tinnitus. I agree it was much worse at night and would wake me up. We cut back my dose. I also got a rash from plaquenil when I went out in the sun. Funny, when I was taking name brand plaquenil, I didn't seem to have any problems, but it got too pricey for my budget. For example Plaquenil Your body then makes a chemical that causes the allergic reaction. So every time you are exposed to the allergan, the body makes the chemical very quickly as it now knows how and you get a rash, or other symptoms. Sjögren's syndrome is an autoimmune condition that can occur at any age, but is most common in older women. Many patients develop Sjögren's syndrome as a complication of another autoimmune disease, such as rheumatoid arthritis or lupus Symptoms vary in type and intensity, but many people with Sjögren's are able to live normal lives.