Fatal dose of chloroquine

Discussion in 'Without A Doctor Prescription' started by Vanchopa, 24-Feb-2020.

  1. registrator_ya XenForo Moderator

    Fatal dose of chloroquine


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Because Chloroquine is cheap, abundant and low risk for short term dosage, it would be ideal as a single pill/weekly dose application to all contacts or people with cold like symptoms. Its about disease modification, not transmission prevention. A metabolite of chloroquine – hydroxychloroquine – has a long half-life 32–56 days in blood and a large volume of distribution 580–815 L/kg. The therapeutic, toxic and lethal ranges are usually considered to be 0.03 to 15 mg/l, 3.0 to 26 mg/l and 20 to 104 mg/l, respectively. Sep 13, 2019 Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Fatal dose of chloroquine

    Chloroquine Phosphate chloroquine phosphate dose., Chloroquine - Wikipedia

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  7. Chloroquine is available in tablets of 250 and 500 mg in generic forms and under the brand name Aralen. The recommended dosage for suppressive prophylaxis is 500 mg once weekly starting 1 to 2 weeks before and continuing for at 4 to 6 weeks after travel to an endemic area.

    • Chloroquine - LiverTox - NCBI Bookshelf.
    • Hydroxychloroquine Side Effects Common, Severe, Long Term..
    • Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs.

    Chloroquine poisoning with fatal outcome is also reported on by Drasch and Eisenmenger. In their case, a woman was being treated for porphyria cutanea tarda and was mistakenly given a single dose of 1250 mg chloroquine instead of the intended dose of 125 mg. Therapeutic oral dose of chloroquine for malaria is 500 mg in once weekly dose, for 3 to 4 weeks, or in daily doses of 250 mg for rheumatoid disease 2. As little as 2-3 g of the chloroquine may be fatal in an adult. The most commonly reported lethal dose for adults is 3 to 4 g. A minimum lethal dose in man is estimated at 30 to 50 mg/kg. Chloroquine poisoning, on the other hand, is well understood due to its widespread use in parts of Asia, Africa and Europe for inducing abortion and attempting suicide.6 9 Animal studies have shown the toxicity profile of chloroquine to be approximately two to three times that of hydroxychloroquine.7 Moreover, fatality rates for chloroquine.

     
  8. justifra XenForo Moderator

    Download PDF Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine (Plaquenil). Plaquenil Hydroxychloroquine Side effects, Images, Uses. Plaquenil Withdrawal – Life As An Anomaly Plaquenil - Side Effects, Uses, Dosage, Overdose.
     
  9. eugene78 Well-Known Member

    Background: The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Case Report Hydroxychloroquine Retinopathy Optometry. Hydroxychloroquine And Chloroquine Screening 2016 AAO. Hydroxychloroquine-induced retinopathy in a 57-year-old woman
     
  10. sav User

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Feb 19, 2020 To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Plaquenil may interact with acetaminophen, cancer medications, tuberculosis medications, birth control pills or hormone replacement therapy, arthritis medications, ACE inhibitors, antibiotics, antifungals, cholesterol medications.

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