One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Mechanism plaquenil Side effects of hydroxychloroquine win Chloroquine 作用 PurposeThe aim of this case series is to raise awareness of the emerging issue of serious retinal damage caused by the prolonged use of hydroxychloroquine HCQ and the importance of adequate and appropriate monitoring of visual function during treatment. Patient and methodsThis is a small retrospective case series of 3 patients on long-term HCQ who developed serious symptomatic retinal toxicity confirmed on imaging and functional testing. ResultsAll 3 patients were treated with HCQ for over. Hydroxychloroquine HCQ is efficacious for various diseases1,2, but can produce “bulls-eye” retinopathy that decreases vision even after discontinuance3,4. Retinopathy can be present in 7.5% of patients after 5 or more years of HCQ treatment, increasing to 20% after 20 years2. The British Society for Rheumatology BSR has published updated guidelines on the prescribing and monitoring of DMARDs, which include recommendations for more intensive screening for retinal toxicity in patients on antimalarials advice represents a significant shift in practice and results in a substantial additional workload for ophthalmology services to undertake and interpret. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Downes sm hydroxychloroquine retinopathy Retina Today - Imaging in Hydroxychloroquine Toxicity., Hydroxychloroquine Ocular Toxicity Lessons Learned The. Buy chloroquine and proguanil bootsPlaquenil wikiReading oct screening results plaquenil Hydroxychloroquine retinal toxicity is far more common than previously considered; an overall prevalence of 7.5% was identified in patients taking HCQ for greater than 5 years, rising to almost 20% after 20 years of treatment. This review aims to provide an update on HCQ/CQ retinopathy. Hydroxychloroquine retinopathy. - Abstract - Europe PMC. Monitoring for retinal toxicity in patients taking.. Hydroxychloroquine - Wikipedia. Heumatologists use hydroxy- chloroquine sulfate Plaquenil, Concordia Pharmaceuticals to treat autoimmune diseases, namely discoid or systemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, and malaria. When taken at high doses and for long dura- tions, hydroxychloroquine has been known to cause parafoveal retinal toxicity. Hydroxychloroquine HCQ retinopathy can result in permanent vision loss. In early stages of HCQ retinopathy, patients are usually asymptomatic with preservation of visual acuity. A recent update of the American Association of Ophtalmology AAO recommendations on screening for chloroquine and hydroxychloroquine retinopathy, suggests to screen patients under AM treatment.