It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Benefits of plaquenil for rheumatoid arthritis Optometric testing for plaquenil toxicity Ingredients hydroxychloroquine Oct 11, 2004 I am not aware of any eye color changes occurring from Plaquenil. Skin changes though occur in 3-10% of people taking Plaquenil. This may take the form of a rash or slight change in skin or hair pigment. The skin pigment change is rare but can look like a suntan. Plaquenil can make fair-skinned people more sensitive to sunburn. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Does any one else have a problem with a foul smelling body odor or thier urine being dark colored and having a foul odor with lupus? I am also diabetic so it could possibly come from that also. Its just very hard to deal with and makes me so concious to be around other people. I also have. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Does plaquenil make your skin dark Lupus-Specific Skin Disease and Skin Problems Johns Hopkins., Plaquenil - Uses, Side Effects, Interactions - Hydroxychloroquine formulationMalarone for chloroquine resistance ncbi Plaquenil belongs to a class of medication often called as disease-modifying antirheumatic drugs known as DMARDs. Antimalarials are used in changing the way your immune system works. Plaquenil medication reduces skin problems in lupus and prevents swelling or pain in arthritis. However, it is still not known exactly how the drug works. Side Effects Common Side Effects of Plaquenil. Body odor with Lupus? DailyStrength. Plaquenil & skin discoloration -. Find information about common, infrequent and rare side effects of Plaquenil Oral. One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin. They often appear brown, black, or black and blue and tend to develop on the legs, especially around the shins. If Aczone is used along with benzoyl peroxide, it may cause a temporary yellow or orange discoloration of the skin and facial hair. Let your doctor know if your symptoms don't improve, or if they.