Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Chloroquine stability in water Hydroxychloroquine risks DHA-PQP vs Chloroquine and Primaquine for Radical Cure of Vivax Malaria in Brazil CuraVivax The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. As primaquine and chloroquine may lead to the onset of symptoms and also intensify or reduce some of the symptoms of malaria, the occurrence of symptoms before and after drug treatment was analyzed with the McNemar's test for paired samples. Jun 29, 2012 Primaquine, as viewed by many clinicians, has its only role in regard to its activity against P. vivax infection. However, since its introduction in the early 1950’s, primaquine has been found to be active against the early liver stages of both P. falciparum and P. vivax malaria. Primaquine is an 8-aminoquinoline and was developed in the 1940. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Primaquine vs chloroquine Compare Chloroquine vs Primaquine -, Side Effects of Chloroquine and Primaquine and Symptom. Chloroquine tabletCan plaquenil help with hairlossCan you take plaquenil with lipitor Chloroquine is a highly effective schizontocide, while primaquine has weaker asexual-stage activity 3 but is the only generally available drug with hypnozoitocidal properties, i.e. it kills dormant liver stage parasites and prevents relapse radical cure 1. Pharmacokinetic Interactions between Primaquine and.. Prophylaxis of Malaria - PubMed Central PMC. Compare Plaquenil vs Chloroquine -. Before the administration of chloroquine, the patient had only a mild skin erythema in the irradiated area, which was consistent with the radiotherapy dose she had received. On day 3 of chloroquine therapy, she developed localized brisk bullous eruptions in the irradiated area, which developed into a patch of fulminant moist desquamation. Primaquine is active as a chloroquine-resistance reverser at concentrations that could be clinically relevant. As primaquine and chloroquine are already used together in the treatment of P. vivax, this is potentially a cheap way of reviving and extending the life of chloroquine. Primaquine is a good choice to treat and prevent malaria in some parts of the world. primaquine only has to be taken once a day. chloroquine is generally safe to use during pregnancy and for children. You can take chloroquine with or without food.