Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Atrovent and plaquenil New plaquenil dosing guidelines HCQ is widely used for the treatment of rheumatic diseases, particularly lupus and RA. It is generally well tolerated, but retinopathy is a concern. Retinopathy is rare, but is sight threatening, generally irreversible and may progress even after cessation of therapy. Hydroxychloroquine is a medicine that is effective in treating various long-term inflammatory disorders of the joints and skin. In general, it is a safe and cost-effective medication, particularly when compared to newer anti-inflammatory medicines which can more significant adverse effects on the body. Macular Society Helpline 0300 3030 111. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Macular society hydroxychloroquine Hydroxychloroquine Plaquenil -, Clinical Guidelines - The Royal College of Ophthalmologists Plaquenil heart rateMassive hydroxychloroquine overdose Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Retinal toxicity associated with chronic exposure to.. Eye screening for patients taking hydroxychloroquine Plaquenil®. Rx Side Effects New Plaquenil Guidelines and More.. Macular toxicity is related to the total cumulative dose rather than the daily dose. Regular eye screening, even in the absence of visual symptoms, is recommended to begin when either of these risk factors occurs. Toxicity from hydroxychloroquine may be seen in two distinct areas of the eye the cornea and the macula. Before Plaquenil treatment begins. You will have a “baseline” eye exam. This measures the health of your eyes and looks for retinal or macular disease. Once a year while taking Plaquenil. After five years of Plaquenil treatment, when retina damage is likely Hydroxychloroquine is a medication used to treat several conditions, including active rheumatoid arthritis, juvenile idiopathic arthritis, discoid and systemic and cutaneous lupus erythematosus, solar urticarial.