Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. History of chloroquine phosphate Propranolol interactions with hydroxychloroquine Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. The most common paraneoplastic syndrome leading to cognitive and behavioral impairment is LE, in which the antibody response is produced against limbic system structures. A paraneoplastic LE PLE may result from antibodies produced from occult cancers 5. LE also occurs without a known cancer 6, 7•, 8•. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and dementia Visual Hallucinations Differential Diagnosis and Treatment, Long-Term Side Effects of Plaquenil for Rheumatoid. Hydroxychloroquine plaquenil couponsHydroxychloroquine sulfate tablets usp uses Dementia is an umbrella term for a plethora of conditions that affect cognitive abilities, including learning and memory. Alzheimer’s disease is the most common form of dementia. Could lupus raise dementia risk?. Immunologically Mediated Dementias. DMARD use is associated with a higher risk of dementia in.. No significant risk of dementia was observed in patients with RA who used bDMARDs compared with their counterparts. However, patients with RA who used hydroxychloroquine, methotrexate, and sulfasalazine exhibited significant risks of dementia, irrespective of cumulative exposure days. Advanced medication management. On eHealthMe, we have been monitoring drugs and supplements since 2008. We continuously gather data and improve our proprietary algorithms to analyze real-world drug outcomes. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America.