Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Levaquin and hydroxychloroquine Will plaquenil show up on a drug screen PREGNANCY AND LACTATION. Hydroxychloroquine is considered safe in all trimesters of pregnancy. Due to the high risk of flare in systemic lupus erythematosus when discontinuing this medication, continued Plaquenil use is advised in these patients during pregnancy. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Hydroxychloroquine is rapidly absorbed from the gastrointestinal tract, and steady-state concentrations are reached after 4–6 weeks; 45% of hydroxychloroquine binds to plasma proteins that are deposited in tissues such as the liver, spleen, kidney, and lung. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine in lactation Plaquenil hydroxychloroquine sulfate dosing, indications., Hydroxychloroquine DermNet NZ Hydroxychloroquine 200 mg tab generic plaquenilSudden blurry vision with plaquenilPlaquenil mefloquinePlaquenil side effects subconjunctival hemorrhage Many drugs are compatible with breastfeeding, but there are limited data on many of the new drugs. in category D, hydroxychloroquine has been used in pregnancy while methotrexate must be avoided. Hormone concentrations drop rapidly postpartum and there is a switch to a pro-inflammatory state. These changes increase the risk of relapse in Immunomodulatory drugs in pregnancy and lactation. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Hydroxychloroquine in lupus pregnancy - Clowse - 2006.. I was diagnosed with RA just over a year ago after the birth of my baby. I've been breastfeeding my little girl, and so they have been able to give me hydroxychloroquine and depmedrone, which although pass through the milk only in very small quantities my consultant said. I'm now trying to wean her, as methotrexate is next on the list! Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydroxychloroquine in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving this medicine. Breastfeeding The medication is generally well-tolerated, and has even been found safe overall for women who are pregnant or breastfeeding. How is This Medication Given? Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases.