As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and mouth, this can result in difficulty breathing and problems with digestive and bowel function. Malaria resistance to chloroquine Does hydroxychloroquine affect osseointegration Hydroxychloroquine with methotrexate Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Difficulty breathing difficulty seeing at night dizziness or fainting fast, pounding, uneven heartbeat feeling that others are watching you or controlling your behavior feeling that others can hear your thoughts feeling, seeing, or hearing things that are not there fever with or without chills general feeling of tiredness or weakness Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer medication Methotrexate. As with most autoimmune illnesses, it is much more common in women than men. Plaquenil and difficulty breathing How lupus affects the lungs and pulmonary system Lupus., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Can i get chloroquine over the counterHydroxychloroquine and white spots on skin In addition to dry eyes and mouth, this can result in difficulty breathing and problems with digestive and bowel function. As with most autoimmune illnesses, it is much more common in women than men. Treatment includes artificial tears and saliva and, in more severe cases, immune blockers such as prednisone, Plaquenil and even the cancer. Why There's More to Sjogren's Syndrome The Dr. Oz Show. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Oral Uses, Side Effects, Interactions.. Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision.