I would think the drug has aggravated a pre-existing condition. There may be another drug that would not cause your GERD. Coding for plaquenil vision exam Does hydroxychloroquine help with fatigue My doctor wants me to start taking Plaquenil tomorrow. I have read some of your comments about nausea, heartburn, indigestion, and hair loss. I am wondering how long it will take to get any of these side effects if at all after I start Plaquenil? One day, one week, one month, one year? Thank. I have been on plaquenil since December and notice heartburn often but it has helped me with really bad flares but not from the everyday pain. I recently had blood work taken and my SED Rate was higher at 51 and my complement total was still high along with my ANA high positive at 0. As far as I know the advice is to make sure that antacids and Plaquenil are taken at least 4 hours apart. If they are taken together - effectiveness decreases but 4 hours apart is OK. Never do tomorrow what you can put off till the day after tomorrow! It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil is the brand name for the prescription drug hydroxychloroquine. What can i take for heartburn with plaquenil Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil I have heard quite a few. - PBC Foundation Plaquenil slows lupusMalaria tablets chloroquineHigh risk drug use icd 10 plaquenilMalaria chloroquine tabletsDoes plaquenil cause high blood pressure It might be a bit of heartburn or gastritis. Make sure though to wait 2 hrs before and 2hrs after taking the plaquenil to take an antacid. Watch that sun. I find I feel worse when I've had too much of it. I'm prone to itching like crazy after too much sun. Are you using a broad spectrum sunscreen and UV protective clothing hat too? Having issues with Plaquenil -. Plaquenil and antacids?. PLAQUENIL To Take or Not To Take?" Lupus Community.. I have been taking plaquenil, generic also, since 2005. Like others say, rare to affect eyes, but can cause blindness that goes away when med is stopped. I have MCTD. He thinks the plaquenil 200mg and Vit D 50,000 units RX every two weeks hopefully will keep me from developing full blown lupus. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. The heartburn/upper gi upset is horrible on plaquenil for me. But I too can't stand the fatigue/joint pain and I know if I give it some more time, plaquenil may be of great help to me. I took only 200 last Monday night and it gave me nasty heartburn.