I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Hydroxychloroquin eye What is the difference between methotrexate and plaquenil We study how severe was Withdrawal syndrome, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Side effects stopping plaquenil Let me tell you what weaning down from Plaquenil is like., Hydroxychloroquine Side Effects, Dosage, Uses, and More Hydroxychloroquine and cyclobenzaprine Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Many people using this medication do not have serious side your doctor immediately if any of these unlikely but serious side effects occur arm/leg/back pain, fast heartbeat, hair loss/color change, mental/mood changes e.g. anxiety, depression, hallucinations, ringing in the ears/hearing loss, worsening of skin conditions e.g. psoriasismedication may infrequently cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time. Chloroquine Aralen This drug has been known to have more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. More in Eye Health. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage.