Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil free Hydroxychloroquine tiredness Is hydroxychloroquine a sulfa drug. Premium Questions. Is Hydroxychloroquine safe and does it have any side effects? MD. i am allergic to sulfa it puts me in upper respiratory failure I am retaining fluid and the doctors can t seem to find any water drug that does not contain. Hydroxychloroquine sulfate Plaquenil is not a sulfa drug. That is a misconception. However, hydroxychloroquine can be associated with serious dermatological side effects including severe rashes and exacerbation of psoriasis. Hi, I was diagnosed with RA and was put on sulfa, my rheumy tried adding mtx but i had awful side effects so am now on hydroxychloroquine and sulfa.this combination worked for anyone? just wondered how other people got on with it. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Can i use of hydroxychloroquine with sulfa allergy Sulfa, Sulfur, Sulfate, Sulfite Which Causes an Allergy?, Plaquenil and Sulfa Allergies" Lupus Community - Support. Plaquenil en españolAralen 250mg I can take brand name Plaquenil the first few weeks cause stomach upset, but if I take the generic - I get a rash, sore throat and it's hard to swallow. Exactly what I get when I took a sulfa drug when I was a child. The generic probably contains sulfa. Also generic drugs can contain a smaller or larger amount of the prescribed ingredients. Allergic reaction to Plaquenil Lupus Forums at The Lupus.. Combination hydroxychloroquine and sulfasalazine - do.. If you are allergic to sulfa drugs does this mean you can't.. The Plaquenil and sulfasalazine allergies manifested exactly the same way, though the sulfa reaction was a bit more severe. I'm also allergic to the sulfonomide, erythromycin, so I think it's fair to say that anything related to sulfa drugs is off the menu. I'm on prednisone and extra antihistamines for two weeks to get things under control. Feb 17, 2009 I just wanted to let you know that I am highly allergic to sulfa drugs and have been on plaquenil for almost 8 years with no problems at all. I did accidentally take a sulfa drug about 5 years ago and still had the horrible reaction so know I'm still allergic even while being on plaquenil. If I have a sulfa allergy from Bactrim, can I take these other drugs? Here’s a list of common sulfa drugs that I get asked about a lot from patients who have had allergic reactions to Bactrim. If you’ve had an allergic reaction to Bactrim, you do not need to routinely avoid these medications, even though they are technically sulfonamide.