It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine moa lupus Chloroquine pretreatment degradation toxicity Plaquenil with valcyte All blood work came back "normal", lupus is in remission/ inactive. Yay! Dr stopped Hydroxychloroquine plaquenil yesterday fearing it is now doing more harm than good. Over all I do feel it may have caused increased anxiety and depression and irritability.however lupus alone can trigger those symptoms I'm sure. As for depression, I think Plaquenil is actually a mild cortical stimulant, so people usually feel peppier because of it. BUT your elevated ferritin may be indicating an underlying inflammatory process. Never known plaquenil to cause anxiety in the years I've taken it, but I have suffered from anxiety attacks as they were known back in the 60s. Might be worth having a word with someone I agree with Suzie For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Does plaquenil cause depression Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Immune & Autoimmune - Lupus plaquenil causing depression. Chloroquine mechanism of action in slePlaquenil pregnancy lupus Find information about common, infrequent and rare side effects of Plaquenil Oral. Common and Rare Side Effects for Plaquenil Oral. Anxiety and Plaquenil Has anyone experienced mood.. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxy Plaquenil CAN affect moods & can cause 'mental changes' in some people u should b able 2 clarify this by reading u're info leaflet in the med packet. I came off hydroxy as I gained no benefit whatsoever & apart from getting near on every side effect from it, became the most s**** bitch ever lol! After several months off of plaquenil, I went back on it, deciding to stick with the 100 mg per day. I have always been very sensitive to meds. Again my fatigue improved and I began to be able to do more. But again- over several months time my anxiety, depression, and sense of distance from personal relationships began to worsen. Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended.