Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Mechanism of action of hydroxychloroquine in fibromyalgia Chloroquine psoriatic arthritis Celebrex and plaquenil Plaquenil and eye photosensitivity The more common side effects that can occur with hydroxychloroquine include headache. dizziness. diarrhea. stomach cramps. vomiting. Hydroxychloroquine Side Effects Get emergency medical help if you have signs of an allergic reaction hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Hydroxychloroquine HCQ, a commonly used antimalarial drug in rheumatic diseases, has shown favorable metabolic effects on both glucose control and lipid profiles. We describe a case of a young woman with type 1 diabetes whose glycemic control was optimized. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Hydroxychloroquine side effects clinial studies Clinical Trials Using Hydroxychloroquine - National Cancer., Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Plaquenil neuropathyPlaquenil and neurotransmitter acetylcholinePlaquenil hypercalcemia Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. A favorable effect of hydroxychloroquine on glucose and.. Effect of hydroxychloroquine on the survival of patients with.. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Clinical trials are research studies that involve people. The clinical trials on this list are studying Hydroxychloroquine. All trials on the list are supported by NCI. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical. This phase I / II trial studies the side effects and best dose of hydroxychloroquine when given together with palbociclib and letrozole before surgery in treating participants with estrogen receptor positive, HER2 negative breast cancer. Hydroxychloroquine is a substance that decreases immune responses in the body.