She sent me to a hematologist, who tested for a number of things that may be causing the platelets to be high. He determined that I had positive ANA with a titer count of 0. 10-2 plaquenil Can yo freeze reconstituted chloroquine Hydroxychloroquine dosing Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Shauna, I'm not a doctor to put it mildly. But Plaquenil could help someone ANA-negative for a few reasons that I've read about. First, maybe you do have positive ANA & positive autoantibodies, but all your bloodwork was done when those levels had fallen. Then there's that rare kind of SLE called Ro-lupus. If you are pregnant or considering becoming pregnant, discuss Plaquenil with your doctors. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped. I am very frustrated because I still have no answers regarding why the ANA count would be so high if I am testing negative for all of these autoimmune diseases. Yet, he said I was negative for the rheumatoid factor as well as a more specific Lupus test (I don't remember exactly what this test was called, something with DNA). How long plaquenil after positive ana Positive ANA 0. - Lupus - MedHelp, Healthboards - Immune & Autoimmune - Lupus Negative ANA Lupus? Chloroquine cardiomyopathy beyond ocular adverse effects If it wasn’t for ADD medication, I’d never get out of bed. This all worsened after my lower back was reconstructed. Dr. Kyriakos Kirou Once the ANA test is positive, it usually remains positive. Therefore, we do not retest for ANA once we have secured a diagnosis of lupus or a related connective tissue disease. Lupus and Testing Questions Answered. Taking Plaquenil for Rheumatoid Arthritis. Do steroids and Plaquenil change the ANA results? Lupus.. How long can you have symptoms of Lupus before tests come back positive - Hello Ladies, thanks for replying. I have been having problems for four years now. I was diagnosed first with Osteoarthritis.then Fibromyalgia. Hello kelpie21, It can be a hard road, can't it? Hydroxychloroquine does take a while to take effect. Arthritis UK gives a figure of around 12 weeks, whilst the American College of Rheumatology says, "symptoms can start to improve after 1-2 months, but it may take up to 6 months before the full benefits are felt". I knew I had Lupus, due to a malaria rash, but I didn't get an official diagnosis written I'm my chart until I was having a bad flare several years later and finally had a positive ANA. My rheumatologist started me on plaquenil and an NSAID way back when I first saw her, even though I wasn't official yet.