Drug of choice for chloroquine resistant malaria in pregnancy

Discussion in 'Canadian Drug' started by BSemen, 11-Mar-2020.

  1. unnamed.pl XenForo Moderator

    Drug of choice for chloroquine resistant malaria in pregnancy


    Please review the following URL and make sure that it is spelled correctly. Atovaquone/Proguanil (Malarone) Adults: 1 adult tablet daily.

    Chloroquine hyperprolactinemia Chloroquine tablet brand name Can a pregnant woman take chloroquine

    Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link Travelers who reject the advice to take prophylaxis, who choose a suboptimal drug regimen such as chloroquine in an area with chloroquine-resistant P. falciparum, or who require a less-than-optimal drug regimen for medical reasons, are at increased risk for acquiring malaria and then needing prompt treatment while overseas. In addition, any of the regimens listed below for the treatment of chloroquine-resistant malaria may be used for the treatment of chloroquine-sensitive malaria. Prompt initiation of an effective regimen is vitally important and so using any one of the effective regimens that is readily at hand would be the preferred strategy.

    This drug should be used during pregnancy only if clearly needed and the benefit outweighs the risk.-According to some authorities: Use is considered acceptable. Begin 1-2 days before travel, daily during travel, and for 7 days after leaving.

    Drug of choice for chloroquine resistant malaria in pregnancy

    All_antimalarial_drugs TUSOM Pharmwiki, Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health CDC

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  6. TRAVEL TO AREAS WITH CHLOROQUINE-RESISTANT MALARIA. Primaquine and tafenoquine should not be used during pregnancy because the drug may be passed transplacentally to a G6PD-deficient fetus and cause hemolytic anemia in utero. Not a good choice for last-minute travelers because drug needs to be started ≥2 weeks before travel.

    • Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health..
    • CDC - Malaria - Diagnosis & Treatment United States..
    • Malaria, treatment Treatment summary BNF content..

    Mefloquine is the agent of choice for chloroquine-resistant areas, and evidence suggests it is not associated with an increased risk to the fetus. Although the atovaquone-proguanil drug combination is not currently recommended for use during pregnancy, limited data suggest that it is not harmful to the fetus. This agent is approved in the United States for the prophylaxis and treatment of mild chloroquine-resistant malaria. It may be a good prophylactic option for patients who are visiting areas with chloroquine-resistant malaria and who cannot tolerate mefloquine. Each tab combines 250 mg of atovaquone and 100 mg of proguanil hydrochloride. Current status of drug-resistant malaria 10 3. Causes of resistance 12 3.1 Definition of antimalarial drug resistance 12 3.2 Malaria treatment failure 12 3.3 Mechanisms of antimalarial resistance 12 3.3.1 Chloroquine resistance 12 3.3.2 Antifolate combination drugs 13 3.3.3 Atovaquone 13 3.4 Factors contributing to the spread of resistance 13

     
  7. exbaner New Member

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