Abigail Adams began her freelance writing career in 2009, teaching others about medical conditions and promoting wellness by writing on online health and fitness publications. She is educated and licensed as a registered nurse, having received her degree from North Georgia College and State University. View Full Profile Patients use metformin HCL to treat type 2 diabetes mellitus. This form of diabetes is non-insulin dependent and the body allows unused sugars to increase in the bloodstream. Metformin works to lower the blood sugar level, but does not affect the production of insulin. Adverse reactions generally decrease with continued use of a medication. Individuals experiencing any side effects that are bothersome or increase in intensity need to contact a physician. Common side effects of metformin HCL include decreased appetite and weight loss, flatulence and gastric distress, according to Mayo Not only has new research told us how metformin really works, but a new biomarker was found that can determine the optimal dose of metformin that should be used to get the best results for each patient. Research from the Johns Hopkins Children’s Center reveals that the drug most commonly used in Type 2 diabetics who don’t need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar — the hallmark of Type 2 diabetes — by regulating the genes that control its production. Investigators say they have zeroed in on a specific segment of a protein called CBP made by the genetic switches involved in overproduction of glucose by the liver that could present new targets for drug therapy of the disease. In healthy people, the liver produces glucose during fasting to maintain normal levels of cell energy production. After people eat, the pancreas releases insulin, the hormone responsible for glucose absorption. Once insulin is released, the liver should turn down or turn off its glucose production, but in people with Type 2 diabetes, the liver fails to sense insulin and continues to make glucose. The condition, known as insulin resistance, is caused by a glitch in the communication between liver and pancreas. Best place to buy viagra online yahoo answers Can you order cialis online Amoxil uses Today it is believed that metformin in the most widely prescribed anti-diabetic drug in the world. It is a drug that shows excellent efficacy with favorable weight and lipid profiles, supporting its use as first-line therapy for type 2 diabetes unless not tolerated or contraindicated. In addition, other beneficial. Metformin, introduced as frontline therapy for uncomplicated Type 2 diabetes in the 1950s, up until now was believed to work by making the liver more sensitive to insulin. The Hopkins study shows, however, that metformin bypasses the stumbling block in communication and works directly in the liver cells. Metformin lowers blood sugar levels below what they would otherwise be after a meal. This is because it intervenes with the liver’s interaction with and production of glucose. Insulin is the body’s way of dealing with blood sugar. Metformin is an insulin-sensitizing drug primarily used to treat diabetes, but it can also be used for fertility. Women with PCOS may benefit from taking metformin alone, along with Clomid, or even during IVF treatment. Exactly how metformin improves fertility is unclear. While metformin may be used for the treatment of infertility, it is not a fertility drug. In fact, using it to treat infertility is considered an off-label use. (In other words, pregnancy achievement is not the original intended purpose of this drug.) What is this medication? To understand what metformin does, you first need to know what insulin resistance is. Insulin resistance is when the body's cells stop reacting to normal levels of insulin. As a result, the body thinks that there is not enough insulin in the system. This triggers the production of more insulin than your body needs. " Metformin belongs to a class of drugs known as biguanide medications and works in several ways. The medicine reduces the amount of sugar made by the liver, limits the amount of sugar absorbed into the body from the diet, and makes insulin receptors more sensitive (helping the body respond better to its own insulin). All of these effects cause a decrease in blood sugar levels. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your Health Savvy programs. Metformin what is it for Metformin Side Effects What You Need to Know Diabetes Strong, New Information on how Metformin Works - Diabetes In Control Where can i buy ciprofloxacinLasix shotBuy lasix in usPrednisolone side effects for dogsViagra dangerous Metformin is a medicine that should be increased or titrated gradually to ease any stomach discomfort when it is first started. How long this takes will depend on what your health care provider prescribes and how you respond to the medication the medication has several doses. Using Metformin to Treat Type 2 Diabetes When You Should Take. Metformin used for PCOS Everything You Need to Know. What is metformin?. An effective oral diabetes medicine used in controlling blood sugar levels is Metformin. It is best suited for people with type 2 diabetes as it improves blood sugar control. Metformin is also combined with insulin or other medicines certain times for people with type 2 diabetes. However Metformin is not used in the treatment of type1 diabetes. Metformin is literally in a class by itself, at least in the United States, where no other member of this family of drugs is available. It is the medication that is used most as a first-line drug treatment for diabetes, and for good reasons. What is Metformin? It is an oral prescription drug that is used to regulate blood glucose in patients with type 2 diabetes. Type 2 diabetes is metabolic disorder that occurs as a result of the body not using insulin effectively.