Chloroquine exocytosis

Discussion in 'Canada Drug' started by monik, 12-Mar-2020.

  1. kpe8eg New Member

    Chloroquine exocytosis


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    EXPERIMENTAL AND MOLECULAR PATHOLOGY 34, 87-93 1981 Exocytosis of Intact Lysosomes from Skeletal Muscle after Chloroquine Treatment W. T. STAUBER,1 J. J. TROUT, AND B. A. SCHOTTELIUS Department of Physiology, West Virginia University Medical Center, Morgantown, West Virginia 26506, and Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242 Received April 2, 1980. Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best. Pharmacological inhibitors of vesicle trafficking possess great promise as valuable analytical tools for the study of a variety of biological processes and as potential therapeutic agents to fight.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    Chloroquine exocytosis

    Chloroquine-induced endocytic pathway abnormalities., Effects of chloroquine on viral infections an old drug.

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  5. Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells. In Oncotarget. 2018 ; Vol. 9, No. 6. pp. 6883-6896.

    • Temozolomide, sirolimus and chloroquine is a new..
    • Pharmacological Inhibitors of Exocytosis and Endocytosis..
    • THE OF Vol. No. of March hy The of in USA. Insulin..

    A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Chloroquine, which is known to be concentrated in intracellular acid vesicles, stimulates the release of porphyrins from yeast. Experiments with normal baker's yeast Saccharomyces cerevisiae and the sec-1 mutant, with suppressed exocytosis, showed that the release of porphyrins was stimulated more in normal yeast than it was in the mutant. It is suggested that chloroquine stimulates the. Variations of endocytic and of lysosomal functions during the cell cycle have been investigated in synchronized hepatoma cells derived from Morris hepatoma 7288c by following the cellular uptake of horseradish peroxidase, dextran mol wt. 70,000, and chloroquine.

     
  6. Bra1ner1ck User

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  7. porutchik New Member

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    Is it safe to take hydroxychloroquine and amitriptyline.
     
  8. Carstopper Well-Known Member

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