Azithromycin use in pregnancy

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    Azithromycin use in pregnancy


    When you’re pregnant and come down with an illness, you’re likely worrying about how the infection could affect your baby. As if that’s not enough, a large study out of the Université de Montréal warns that there are concerns around some of the antibiotics you may need to get better. Researchers found that many antibiotics used to treat infections are associated with an increased risk of miscarriage when taken in early pregnancy. The study, which was published in the showed the antibiotics azithromycin, clarithromycin, metronidazole as well as whole classes of antibiotics (sulfonamides, tetracyclines and quinolines) increased the risk of miscarriage when taken before the 20th week of pregnancy. Depending on the drug, the miscarriage risk increased by 65 percent to more than double. The problematic antibiotics are used to treat STIs, skin infections, respiratory infections and more. In fact, those that are most often prescribed to treat infections in pregnant women—penicillins and cephalosporins—were not associated with a higher miscarriage rate. This is not the first study to link antibiotics during pregnancy to miscarriage, but the evidence so far has been mixed. Researchers found that two of the most commonly used antibiotics -- azithromycin and clarithromycin -- are safe for women to take during pregnancy. Both drugs belong to a group of antibiotics called macrolides, which include in their molecular structure a macrocyclic lactone ring with one or more sugars attached. Antibiotics from this family of drugs often are used in place of drugs such as penicillin if patients are allergic to them. The study was mounted because of a long-standing debate on the threat to health and development antibiotics may pose to pregnant women and fetuses. "With penicillin, macrolides are amongst the most used medications in the general population and in pregnancy. However, debate remained on whether it is the infections or in fact the macrolides used to treat them that put women and their unborn child at greater risk of adverse pregnancy outcomes, including birth defects," said Dr. Anick Bérard, a researcher at the of the University of Montreal, in a press release.

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    Azithromycin is a prescription medication used to treat many bacterial infections such as those of the lungs and airways, eyes, ears, sinuses, skin, throat, and infections from sexually transmitted diseases. Azithromycin should be used during pregnancy only if clearly needed. For example, tetracyclines can discolor a developing baby's teeth. Tetracyclines aren't recommended for use after the 15th week of pregnancy. Jan 31, 2017. safety data on antimicrobial use in pregnancy and lactation and is to be. Due to the fact that low levels of azithromycin are detected in breast.

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    Azithromycin use in pregnancy

    Taking certain antibiotics during pregnancy may increase your risk of., Antibiotics and pregnancy What's safe? - Mayo Clinic

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    • Azithromycin - Bumps.
    • Antimicrobial safety In Pregnancy and Lactation - HSE.
    • Azithromycin and third trimester - InfantRisk Forums.

    Advice and warnings for the use of Azithromycin during pregnancy. FDA Pregnancy Category B - No proven risk in humans. Oct 30, 2015. Azithromycin and clarithromycin, commonly used in place of penicillin for. and clarithromycin -- are safe for women to take during pregnancy. Now, the researchers want to possibly shift the focus of treatment the use of. May 5, 2017. In a study of 182,000 pregnant women, the use of certain antibiotics. Several of these, like azithromycin and ciprofloxacin, are commonly.

     
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