Specifically in Mopani, Vhembe, and Waterberg district municipalities of Limpopo Province; Ehlanzeni district municipality in Mpumalanga Province; and Umknanyakude in Kwazulu-Natal Province. Present in the municipality of Tapanahony in Sipaliwini Province. Rare cases in Brokopondo Province, Marowijne Province, and Boven Saramacca municipality in Sipaliwini Province. Factors that affect local malaria transmission patterns can change rapidly and from year to year, such as local weather conditions, mosquito vector density, and prevalence of infection. Hydroxychloroquine burrelia burgdorferi Hydroxychloroquine rheumatoid arthritis Chloroquine cytotoxic hemozoin falicparum Hydroxychloroquine natural killer cells Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Choosing a Drug to Prevent Malaria. Considerations when choosing a drug for malaria prophylaxis Recommendations for drugs to prevent malaria differ by country of travel and can be found in Malaria Information by Country. Recommended drugs for each country are listed in alphabetical order and have comparable efficacy in that country. No. Estimated relative risk of malaria for US travelers Drug resistance 4 Chloroquine. Malaria species P. falciparum 90%, P. vivax 5%, P. ovale 5%. Recommended chemoprophylaxis Areas in Limpopo, Mpumalanga, and Kwazulu-Natal Provinces with malaria Atovaquone-proguanil, doxycycline, mefloquine, or tafenoquine. 4. Other Vaccines to Consider Several medications are available for chemoprophylaxis. When deciding which drug to use, consider specific itinerary, length of trip, cost of drug, previous adverse reactions to antimalarials, drug allergies, and current medical history. Information in these tables is updated regularly.4. Chloroquine malaria prophylaxis Chloroquine - StatPearls - NCBI Bookshelf, CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria Chloroquine hydroxychloroquine quinPlaquenil severe rash Red Pages Malaria Information and Prophylaxis, by Country. Links with this icon indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention CDC cannot attest to the accuracy of a non-federal website. Malaria Information and Prophylaxis, by Country S - CDC. Yellow Fever Vaccine & Malaria Prophylaxis Information, by.. Prophylactic use of antimalarials during pregnancy. When chloroquine, doxycycline, or mefloquine is used for primary prophylaxis, primaquine is usually taken during the last 2 weeks of postexposure prophylaxis. When atovaquone-proguanil is used for prophylaxis, primaquine may be taken during the final 7 days of atovaquone-proguanil, and then for an additional 7 days. Chloroquine should not be used for treatment of P. falciparum infections acquired in areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Patients infected with a resistant strain of plasmodia as shown by the fact that normally adequate doses have failed to prevent or cure clinical malaria or parasitemia should be treated with another form of antimalarial therapy. Chloroquine is used as prophylaxis for malaria. Malaria Chloroquine is used in the treatment of malaria characterized by muscle pain, fever with chills and fatigue.