Letrozole is an aromatase inhibitor that is utilized to decrease the risk of breast cancer recurrence. However, it was discovered that its anti-estrogenic properties actually make it useful for fertility enhancement. The initial decline in estrogen stimulates the pituitary gland to secrete FSH which encourages the egg(s)/follicle(s) to develop. While letrozole works similarly to CC in terms of inducing ovulation, there are several important differences. Letrozole is cleared from the body more quickly than CC and has less negative effects on the endometrial lining and cervical mucous. Some women who fail to ovulate with CC may respond to letrozole. For fertility purposes, the usual dose is one to two tablets daily for 5 days generally beginning day 3, 4, or 5 of the cycle. The most common side effects of letrozole include hot flashes, headaches, muscle or joint pain, fatigue, nausea or swelling of the hands/feet. The risk of twins is increased with the use of letrozole but is thought to be less common than with CC. Human chorionic gonadotropin (h CG) is required to ripen the follicles and make ovulation occur. In the first form, h CG is packaged as 10,000 international units of drug as a dry powder. In the second formulation, now used more commonly, h CG is available in premixed syringes for subcutaneous administration. It causes the pituitary gland to release hormones needed to stimulate ovulation (the release of an egg from the ovary). Clomiphene is used to cause ovulation in women with certain medical conditions (such as polycystic ovary syndrome) that prevent naturally occurring ovulation. Clomiphene may also be used for purposes not listed in this medication guide. You should not use clomiphene if you have: liver disease, unexplained abnormal vaginal bleeding, an uncontrolled adrenal gland or thyroid disorder, an ovarian cyst (unrelated to polycystic ovary syndrome), or if you are pregnant. You should not use clomiphene if you are allergic to it, or if you have: Do not use clomiphene if you are already pregnant. Talk to your doctor if you have concerns about the possible effects of this medicine on a new pregnancy. Clomiphene can pass into breast milk and may harm a nursing baby. This medication may slow breast milk production in some women. Using clomiphene for longer than 3 treatment cycles may increase your risk of developing an ovarian tumor. Higher doses of clomiphene can also lead to visual disturbances, which may be irreversible, or a condition called ovarian hyperstimulation syndrome (OHSS). Symptoms include abdominal pain, bloating, nausea, weight gain, and trouble breathing. Your doctor may occasionally change your dose to make sure you get the best results.
“Infertile couples from all over the world come to St. Sherman Silber and his team are simply the best there is.” – Discovery Health Channel Documentary Unfortunately IVF has become so popular as a treatment for infertile couples, that sometimes without adequate supervision or serious regulation, some small “IVF” centers are opening up in little doctors’ office buildings, and non-experts or newly self-proclaimed “fertility doctors” are delivering the IVF care. It is best to look for IVF in a setting of a major quality medical center that is more concerned about the practice of good medicine than about your pocketbook and which has invested heavily in high standards “clean room” air purification systems. IVF (in vitro fertilization) is the most common form of ART (Assisted Reproductive Technology). If the fallopian tubes are damaged or the sperm is poor, it is obviously the only acceptable treatment. It is also usually the most effective treatment for most other types of infertility as well. The eggs are fertilized in our laboratory, and the resulting embryos then are placed into the uterus 2 to 5 days later. This procedure achieves remarkable pregnancies even in women with hopelessly damaged fallopian tubes, seemingly sterile husbands, and even “unexplained” infertility. Problems with the husband’s sperm are never a serious issue, since we can fertilize the eggs with ICSI. By Shawn (California) I'm 37 and I have a left hydrosalpinx which was cauterized and aspirated I also have a couple of fibroids that have been checked shouldn't cause any problems, because of the fibroids what fertility option do you think is best Clomid or IVF? Answer: Since you are only 37, I would recommend natural health while you make the decision. I can tell you that you still have a chance of getting pregnant naturally. I know that you might have been told otherwise, but the rate of success of IVF is not 100% and with Clomid you have the risks of ovarian hyperstimulation syndrome and other side effects. Since you have been diagnosed with lateral hydrosalpinx, you still have one functional fallopian tube. I know of many cases where women got pregnant naturally having only one ovary or one fallopian tube. Hydrosalpinx is a blocked fallopian tube with fluid the prevents the sperm to pass, the egg to be picked up and of course, fertilization to occur. The major causes of hydrosalpinx is pelvic inflammatory disease like Chlamydia, Gonorrhea and tubal tuberculosis.
Clomiphene is oral medication commonly used in the treatment of infertility that stimulates ovulation. Clomiphene Instructions for Princeton IVF patients. Please start the clomid on day 3 of your cycle. With minimal IVF, the oral medication clomiphene citrate Clomid and low doses of injectable hormones are used to obtain a small number of eggs and avoiding.