Sertraline is used for a number of conditions, including major depressive disorder (MDD), obsessive–compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD. Sertraline used for the treatment of depression in elderly (older than 60) patients was superior to placebo and comparable to another SSRI fluoxetine, and TCAs amitriptyline, nortriptyline (Pamelor) and imipramine. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline. In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. placebo in elderly patients showed a statistically significant (that is, unlikely to occur by chance), but clinically very modest improvement in depression and no improvement in quality of life. A meta-analysis on SSRIs and SNRIs that look at partial response (defined as at least a 50% reduction in depression score from baseline) found that sertraline, paroxetine and duloxetine were better than placebo. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Zoloft (sertraline chloride) is one of the most popular SSRI antidepressants on the market. Pfizer developed and marketed Zoloft as a safer alternative with fewer side effects and withdrawal symptoms than competitor drugs such as Eli Lilly’s Prozac. Zoloft treats a wide variety of psychiatric disorders, but it may also cause birth defects, suicidal thoughts, autism and withdrawal symptoms. under the brand name Lustral, and it took nine years for Americans to gain access to it. In that same year, it was the sixth most prescribed brand-name prescription medication, grossing nearly $ 3.3 billion. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. By 2005, Zoloft was the most popularly prescribed antidepressant on the U. Pfizer lost the Zoloft patent in 2006, but announced that it would manufacture a generic version through its Greenstone division.
Zoloft (sertraline) is an antidepressant medication is a member of the serotonin-specific reuptake inhibitor (SSRI) class, which works by increasing serotonin levels in the brain. Though Zoloft was intended to be safer than older medications, it has been shown to increase the risk of suicide, birth defects and other serious side effects. The FDA has issued multiple warnings about Zoloft and has required changes to its prescribing information and Pfizer, Zoloft’s manufacturer, has faced lawsuits for injuries caused by the medication. Zoloft Zoloft is the brand name of the generic medication, sertraline. It is a member of the SSRI class of antidepressants and is approved for major depression, anxiety and panic disorders, post-traumatic stress disorder and premenstrual dysphoric disorder in adults and for obsessive-compulsive disorder in adolescents and adults. It has also been used “off-label” for bipolar disorder, premature ejaculation, headaches and other conditions. Neurotransmitters like norepinephrine, dopamine and serotonin are used as chemical messengers by the brain cells. Consumer Medicine Information This leaflet answers some common questions about Zoloft. It does not take the place of talking to your doctor or pharmacist. Your doctor has weighed the risks of you taking Zoloft against the benefits it is expected to have for you. Zoloft is used to treat depression and conditions called obsessive compulsive disorder (OCD), panic disorder, social phobia (social anxiety disorder) and premenstrual dysphoric disorder (PMDD). If you have any concerns about taking this medicine, ask your doctor or pharmacist. PMDD affects some women in the days before their period. PMDD is different from premenstrual syndrome (PMS). The mood symptoms (anger, sadness, tension, etc) in PMDD are more severe than in PMS and affect the woman's daily activities and relationships with others. Zoloft belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). They are thought to work by blocking the uptake of a chemical called serotonin into nerve cells in the brain. Serotonin and other chemicals called amines are involved in controlling mood.
Learn about Zoloft Sertraline Hcl may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Sertraline is used to treat depression, obsessive-compulsive disorder OCD. an increased risk of certain side effects but may be unavoidable in some cases.