I've posted in a separate thread about my new diagnosis. I've noticed since I've started taking Metformin that I've been oddly moody and a bit more depressed than normal this past week. I'm doing some research online right now but wondered of other people's encounters with this drug. The last thing I want right now is to feel emotionally worse than I already do. Perhaps after some time, my body will get used to it. Could this just be a side effect of starting the new medication? I haven't noticed any emotional problems per se with metformin. Most people have gastric problems for a little while, Butter Butt and I get leg pain from it after a while, but mine is manageable as long as I take a b complex supplement. Another reason for emotional ups and downs may be the new diagnosis, ( stages of grieving) and dietary changes, so good supplements may be helpful. Online Drug Store Bangladesh - Desert Eye But there is no mention in the old literature of the endocrine form of laminitis, the type most commonly seen today. Order Cheap Medications At The Best Prices Horse Health Products And Supplies - Animed Direct Linked to elevated levels of insulin in the blood, this type is usually seen in horses with EMS or PPID. Animed supply a great range of horse and pony products. We understand that the health and well being of your pet is of utmost importance, so as one of the UK's leading pet dispensary stores Animed Direct offer you the chance to buy your pet medicines at affordable prices. - The Horse Owner's Resource If the item comes direct from a manufacturer, it may be delivered in non-retail packaging, such as a plain or unprinted box or plastic bag. A recent study showed the drug Metformin, which is used in people to lower blood sugar, caused a dramatic increase in one type of the bacteria in the GI tract. This drug is also used in horses but is known to be poorly absorbed by the horse's circulatory system, raising questions about its effectiveness.
Equine Insulin Resistance is high Insulin levels with normal Glucose levels. “If lactic acidosis does occur, it can be – used young thoroughbreds and standardbreds that were normal AND which are not even Insulin Resistant. Metformin reduces Thyroid stimulating hormone in cases of underactive Thyroid – up to a 55% increased risk of low TSH. Click here for 2014 Article about Metformin Causing Thyroid and Heart Problems, from the United Kingdom. But Metformin is a human Diabetes drug that has one job – to lower Glucose. Click here for American Diabetes Association Study, Dr. It makes no sense to give a drug to lower Glucose in a horse with already normal Glucose. Oregon State’s Veterinary Research Team in May 2009 found this drug is not absorbed by horses. Metformin is for Type 2 Diabetes which most horses never get. It is going in one end and out the other and so is your time and money. No FDA approval for use in horses – creates liability issues. One small study in England, years ago, thought they saw effect, but no university or institute can replicate these findings. Conclusions of the Study: only 4-7% of Metformin giving orally 2 times a day is absorbed and is “insufficient to achieve plasma concentrations of drug comparable to the therapeutic range achieved by humans.” AJVR 2009, May, Dr. This study was before Oregon State’s Veterinary School found the drug was not even being absorbed in any useful manner. Requires constant/multiple blood testing to monitor. Also, the English study tried 2 times per day dosing which is difficult on clients. “At some point this medicine may stop working and your blood glucose will increase.” Mayo Clinic, 2008.10. “Carry an Emergency ID Card and Glucagon Emergency Kit for emergencies” due to hypoglycemic reactions. “Recent research shows a lack of efficacy of the drug on Insulin Resistance”17. In horses, there's little doubt that high-carbohydrate feeding influences the response to insulin, but it's more complicated than in people or other animals. The horse evolved without any sources of concentrated carbohydrate in its diet. When horses are grain fed, their responsiveness to an intravenous injection of insulin drops, i.e., less insulin sensitive, more insulin resistant — yet their ability to keep blood glucose in control is usually well preserved. Insulin Resistance (IR) in ponies was reported almost 40 years ago. IR in horses was recognized less than 15 years ago. However, a 1989 USDA-sponsored survey found that 13% of the owners and equine premises surveyed reported having laminitis problems in the prior 12 months. Laminitis was second only to colic as a reason for seeking veterinary care.
Prior to IR and Equine Metabolic Syndrome coming into the limelight as the " disease du jour", it was very. Metformin was tried in horses in one small US study. Horse Health Products And Supplies - Animed Direct Linked to elevated levels of insulin in the bloodA recent study showed the drug Metformin, which is used in people to lower blood sugar, caused a.