The NICE British National Formulary (BNF) and British National Formulary for Children (BNFc) sites are only available to users in the UK, Crown Dependencies and British Overseas Territories. If you believe you are seeing this page in error please contact us. The parenteral administration of furosemide is indicated in cases where oral administration is not feasible or not efficient (for example in case of reduced intestinal absorption) or when a quick effect is required. To achieve optimum efficacy and suppress counter-regulation, a continuous furosemide infusion is generally to be preferred to repeated bolus injections. Where continuous furosemide infusion is not feasible for follow-up treatment after one or several acute bolus doses, a follow-up regimen with low doses given at short intervals (approx. 4 hours) is to be preferred to a regimen with higher bolus doses at longer intervals. Generally, Furosemide should be administered intravenously. Intramuscular administration must be restricted to exceptional cases where neither oral nor intravenous administration is feasible. It must be noted that intramuscular injection is not suitable for the treatment of acute conditions such as pulmonary oedema. In the absence of conditions requiring a reduced dose (see below) the initial dose recommended for adults and adolescents over 15 years, is of 20 mg to 40 mg furosemide by intravenous (or in exceptional cases intramuscular) administration; the maximum dose varying according to individual response. In either case, the rate of infusion should not exceed 4mg/minute.
Close medical supervision and dose evaluation are required. Watch for and correct electrolyte disturbances; adjust dose to avoid dehydration. When electrolyte depletion is present, therapy should not be initiated unless serum electrolytes, especially potassium, are normalized. In cirrhosis, avoid electrolyte and acid/base imbalances that might lead to hepatic Oral tablet: 47-64%; Oral solution: 60%; S. administration of tablet: ~60%; results of a small comparative study (n=11) showed bioavailability of SL administration of tablet was ~12% higher than oral administration of tablet ( may repeat the same dose or increase dose in increments of 20-40 mg/dose at intervals of 6-8 hours; usual maintenance dose interval is once or twice daily; may be titrated up to 600 mg/day with severe edematous states. injections may be administered at a rate of 20-40 mg per minute; maximum rate of administration for short-term intermittent infusion is 4 mg/minute; exceeding this rate increases the risk of Assess for allergy to sulfonylurea before beginning therapy. Initial: 20-40 mg/dose; if response not adequate, may repeat the same dose or increase dose in increments of 20 mg/dose and administer 1-2 hours after previous dose (maximum dose: 200 mg/dose). Assess potential for interactions with other pharmacological agents or herbal products patient may be taking (especially anything that may impact fluid balance, electrolyte balance, or increase potential for or hypotension). Assess results of laboratory tests (electrolytes), therapeutic effectiveness, and adverse response on a regular basis during therapy (, dehydration, electrolyte imbalance, postural hypotension). Individually determined dose should then be given once or twice daily although some patients may initially require dosing as frequent as every 6 hours. Caution patients with diabetes about closely monitoring glucose levels (glucose tolerance may be decreased). Initial: 1 mg/kg/dose; if response not adequate, may increase dose in increments of 1 mg/kg/dose and administer not sooner than 2 hours after previous dose, until a satisfactory response is achieved; may administer maintenance dose at intervals of every 6-12 hours; maximum dose: 6 mg/kg/dose I. Teach patient appropriate use, possible side effects/appropriate interventions, and adverse symptoms to report. This leaflet answers some common questions about Lasix oral medicines (tablets, oral solution) and injections. It does not take the place of talking to your doctor or pharmacist. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will have for you. Lasix contains furosemide (frusemide), which belongs to a family of drugs called diuretics. If you have any concerns about taking this medicine, ask your doctor or pharmacist. A diuretic helps reduce the amount of excess fluid in the body by increasing the amount of urine produced. Lasix is used to treat swelling of the ankles, feet, legs or even the brain or lungs. This swelling is called oedema and can occur in some heart, lung, liver or kidney conditions. Lasix may be used in some patients with more serious kidney problems who may have some fluid retention. Lasix may also be used to lower high blood pressure (which is also called hypertension). This pressure helps move your blood around your body. Your blood pressure may vary at different times of the day, depending on how busy or worried you are.
Furosemide oral tablet is a prescription drug that’s available as the brand-name drug Lasix. Furosemide is used to treat hypertension (high blood pressure). Furosemide may be used as part of a combination therapy to treat high blood pressure. In some cases, they may not be available in every strength or form as the brand-name version. Edema can be caused by other medical conditions such as heart failure, cirrhosis of the liver, or kidney disease. This means you may need to take it with other medications. Furosemide belongs to a class of drugs called diuretics. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Furosemide works by helping your body get rid of excess salt and water. Take this medicine exactly as directed by your doctor to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Many patients who have high blood pressure will not notice any symptoms of the condition. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. In addition to using this medicine, treatment of your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt) or potassium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet. This medicine will not cure your high blood pressure, but it does help control it.
Lasix Furosemide drug is used to eliminate extra water and salt in. These changes may require your doctor to reevaluate your dosage. Medscape - Hypertension-specific dosing for Lasix furosemide, frequency- based adverse effects, comprehensive interactions, contraindications, pregnancy.