Nortriptyline, part of the class of drugs known as tricyclic antidepressants, is often used as a preventative to fight chronic pain. Obviously, as an antidepressant, it’s commonly used to treat symptoms of depression. It works in the chemicals of the brain by inhibiting the reuptake of norepinephrine (noradrenalin) and serotonin. It’s commonly sold under the brand names Aventyl, Pamelor, Norpress, Allegron, Sensoval, and Nortrilen. But nortriptyline hydrochloride (commonly misspelled as nortriptilyne) has long been used for a variety of other conditions. Some commonly go along with migraine, such as irritable bowel syndrome, fibromyalgia, and TMJ disorder. But it is also used to treat chronic pain, particularly the pain of migraine and tension-type headache, but also cancer pain and arthritic pain. Migraine is a very common, but very particular, type of headache. Most people who have migraine experience repeated attacks of headaches that occur over many years. The typical migraine headache is throbbing or pulsating, and often is associated with nausea and changes in vision. While many migraine headaches are severe, not all severe headaches are migraines, and some episodes can be quite mild. Up to 20% of people in the United States will experience migraine headaches at some point in life. In about half of those, migraine headaches first appear during childhood or adolescence. Two-thirds of people who get migraines are women, probably because of the influence of hormones. Despite years of research, scientists do not know exactly why migraines occur.
Also known as: Hemangeol, Inderal LA, Inderal XL, Inno Pran XLThe following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."I have been taking 80 mg of Propranolol per day for about 5 years for Migraine Prevention and High Blood Pressure. It's an added bonus for me that it also treats anxiety. I've always had mild anxiety and I blush very easily. I hardly get migraines now and I do feel calmer which is great since I had just begun to worry incessantly about my 3 kids, especially now that they are teenagers. In the beginning it made me tired but about 2 weeks later I got use to it. I believe I also have a bigger appetite and have gained about 10 pounds but to me it is worth it! Beta Blockers in the Treatment of Migraine Of all the preventative medicines available across the United States, the drugs known as beta blockers are probably the most frequently prescribed. The "beta" refers to receptors on the blood vessels known as beta receptors. Beta blockers prevent the chemical interaction of certain chemicals with this receptor, hence, the term "beta blockers." Of this family of drugs, the most frequently used drug is Inderal, although others, such as Tenormin and Corgard, will also be used occasionally. Beta blockers were developed primarily for control of cardiac symptoms, but it was found coincidentally that these drugs had a remarkable effect on migraine prevention. After this chance observation was made, studies conducted in the late 1960s and early 1970s confirmed the improvement in migraine with treatment. The studies show that sixty to seventy percent of all migraine subjects experienced a decrease of more than fifty percent in the incidence and severity of their headaches when treated with one of these beta blockers. Two beta blockers are currently FDA approved for use in the preventative treatment of migraine: propranolol (Inderal and Inderal LA) and timolol (Blocadren).
Inderal, a type of medication known as a beta blocker, is used in the treatment of high blood pressure, angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries), changes in heart rhythm, prevention of migraine headache, hereditary tremors, and tumors of the adrenal gland. Inderal is also used to reduce the risk of death from recurring heart attack. Recommended dosage, how much to take ADULTS: All dosages of Inderal, for any problem, must be tailored to the individual. Your doctor will determine when and how often you should take Inderal. If you are over 65, the doctor will probably start with a relatively low dosage. Inderal is also available in a sustained-release formulation, called Inderal LA, for once-a-day dosing. Inderal dosage for hypertension, high blood pressure The usual starting dose is 40 milligrams 2 times a day. Dosages above 80 mg a day increase the risk for side effects. When used for the treatment of high blood pressure, Inderal is effective alone or combined with other high blood pressure medications, particularly thiazide-type diuretics. Sufficient evidence and consensus exist to recommend propranolol, timolol, amitriptyline, divalproex, sodium valproate, and topiramate as first-line agents for migraine prevention. There is fair evidence of effectiveness with gabapentin and naproxen sodium. Botulinum toxin also has demonstrated fair effectiveness, but further studies are needed to define its role in migraine prevention. Limited evidence is available to support the use of candesartan, lisinopril, atenolol, metoprolol, nadolol, fluoxetine, magnesium, vitamin B (riboflavin), coenzyme Q10, and hormone therapy in migraine prevention. Data and expert opinion are mixed regarding some agents, such as verapamil and feverfew; these can be considered in migraine prevention when other medications cannot be used. Evidence supports the use of timed-release dihydroergotamine mesylate, but patients should be monitored closely for adverse effects. 2 Preventive therapy, which can reduce the frequency of migraines by 50 percent or more, is used by less than one half of persons with migraine headache.3Following appropriate management of acute migraine, patients should be evaluated for initiation of preventive therapy.
User Reviews for Propranolol systemic. Also known as Hemangeol, Inderal LA, Inderal XL, InnoPran XL. The following information is NOT intended to endorse drugs or. I started Nortriptyline and Topiramate years ago through my neurologist at Kaiser. For horrible Migraines affiliated with chronic neck pain. I am a 20 year chronic.