Propranolol withdrawal syndrome

By: diavolos Date: 13-Feb-2019
Mechanism of <i>propranolol</i> <i>withdrawal</i> phenomena. - AHA Journals

Mechanism of propranolol withdrawal phenomena. - AHA Journals

Exploding head syndrome (EHS) is a disorder characterized by the perception of loud noises (e.g. a bomb explosion, gunshot or cymbal crash) when going to sleep or awakening. Contrary to the name, ENS is not associated with pain. However the noise attacks can elicit a great deal of fear, confusion and distress in sufferers. Reports of tachycardia and palpitations are also common. Despite the distressing nature of EHS, relatively little is known about the prevalence and underlying cause of the condition. Some scientists have estimated that EHS may affect 10% of the population. RLS is defined by four essential criteria needed for clinical diagnosis which are established by the International Restless Legs Syndrome Study Group. The urge to move the legs, usually accompanied or caused by uncomfortable and unpleasant sensations in the legs. Symptoms are partially or totally relieved by movement such as walking or stretching. Symptoms are worse at night with periodic limb movements. adult population is affected by restless legs syndrome and it is more common in women. While symptoms can vary from person to person, they are generally described as an urge to move the legs accompanied by burning, creeping, crawling, aching, tingling, or tugging sensations in the legs. As a direct result patients may experience daytime tiredness, mood disturbance, and inability to perform daily activities, which can have a substantial negative impact on quality of life. The dopamine neurotransmitter system appears to be mostly involved with this condition. Restless legs syndrome is mostly thought of as a condition that affects adults, but it is also fairly common in children and teenagers. Older men who suffer from RLS at night are almost twice as likely to have erectile dysfunction as those without the condition. The mechanisms underlying the association between RLS and erectile dysfunction could be caused by hypofunctioning of the brain chemical dopamine in the central nervous system, which is associated with both conditions.

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INTRODUCTION — Alcohol use is a global health concern, ranking seventh among the leading causes of death and disability such, most clinicians are forced to confront its complications in some of their patients. There are an estimated eight million alcohol-dependent people in the United States alone, and approximately 500,000 episodes of withdrawal severe enough to require pharmacologic. A startup wants to create a platform for people anxious about public speaking to get prescriptions for a cardiac drug that can calm racing hearts.

Propranolol withdrawal syndrome
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